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Raman micro flow cell

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Raman flow assembly connected to an
Specs at a glance
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Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish
Adhesive: USP Class VI and ISO 10993 compatible -
Sterilization method
CIP/SIP
Field of application
The Raman flow cell meets the speed demands of downstream by optimizing Raman collection for low-turbidity, low volume samples. Ideally suited for development-scale flow rates, the Raman flow cell allows real-time monitoring, rapid process optimization, and process control for chromatography and other downstream unit operations.
Downstream: aggregation, protein crystallization, formula stability, product CQA, protein concentration, buffer excipients
Benefits
The
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity

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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
FLEX selections | Technical excellence | Simplicity |
---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
|
Simplicity
|
Lean selection Handle your core processes easily |
Technical excellence
|
Simplicity
|
Extended selection Optimize your processes with innovative technologies |
Technical excellence
|
Simplicity
|
Xpert selection Master your most challenging applications |
Technical excellence
|
Simplicity
Variable |
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Measuring principle
Raman Spectroscopy
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Temperature
Operating:
0 to 40 °C / 32 to 104 °F
Storage:
-20 to 60 °C / -4 to 140 °F -
Relative humidity
Storage:
< 90 % Non-Condensing -
Unit dimensions (width x height x depth)
46 x 25 x 11 mm
1.8 x 1.0 x 0.4 inch -
Sampling probe compatibility
Raman Rxn-10
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Sampling optic compatibility
micro flow bench
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Pressure
Max pressure: 4.8 barg / 70 psig
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Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Surface finish: Ra 15 with Electropolish to ASME BPE SF4 finish
Adhesive: USP Class VI and ISO 10993 compatible -
Sterilization method
CIP/SIP
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Process connection
5/16-24 flat bottom ferrules
Up to 3/16 inch OD tubing -
Fluid path thickness
2.5 mm
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Flow conditions
Laminar
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Flow cell maximum volumetric flowrate
15 mL/min
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Technical Information (TI)
Raman flow assembly Technical Information
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Technical Information (TI)
English version - 06/2023System design and specifications for the Raman flow assembly
(KRFB, KRFC)EN 30/06/2023Language:
English
Version:
30/06/2023
File size:
329.5 KB
File name:
TI01721CEN_0123.pdf
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Technical Information (TI)
Raman flow assembly calibration and verification kit Technical Information
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Technical Information (TI)
English version - 06/2023System design and specifications for the Raman flow assembly calibration
and verification kitEN 29/06/2023Language:
English
Version:
29/06/2023
File size:
430.9 KB
File name:
TI01720CEN_0123 Raman flow assembly calibration and verification kit.pdf
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Operating Instruction (BA)
Raman flow assembly Operating Instructions
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Operating Instruction (BA)
English version - 06/2023Commissioning, operation, and maintenance details for the
Raman flow assembly (KRFB, KRFC)EN 30/06/2023Language:
English
Version:
30/06/2023
File size:
951.5 KB
File name:
BA02296CEN_0123.pdf
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Operating Instruction (BA)
Raman flow assembly calibration and verification kit Operating Instructions
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Operating Instruction (BA)
English version - 06/2023Commissioning, operation, and maintenance details for the
Raman flow assembly calibration and verification kitEN 29/06/2023Language:
English
Version:
29/06/2023
File size:
1006.6 KB
File name:
BA02295CEN_0123 Raman flow assembly calibration and verification kit.pdf
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PU (Publication)
Biopharma 4.0 model graphic
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PU (Publication)
English version - 05/2025Graphic illustrating the core elements of Biopharma 4.0 including
product lifecycle stages, role of PAT/QbD, and 12 key advanced
technologies for scientists and process engineers in the Life
Sciences, applicable to Raman spectroscopy systems (Raman
Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and
sleeve, flow cell and flow bench, Raman optic system for single
use, and Raman calibration & verification kits).Language:
English
Version:
22/05/2025
File size:
481.6 KB
File name:
PU01614CEN_0125.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
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PU (Publication)
Czech version - 09/2024This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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PU (Publication)
Endress+Hauser - ライフサイエンス技術のワンストップパートナー
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PU (Publication)
Japanese version - 10/2024Endress+Hauserが、ライフサイエンス分野の専門知識と、ラマン分
光システム(Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45、Rxn-46、
バイオマルチオプティックおよびスリーブ、フローフィル、フロー
ベンチ、シングルユース用Ramanオプティックシステム)や水質分
析センサ技術(Liquiline CM44P、CM442、OUSAF44、OUSBT66、
Memosens CPS61E、CLS82E、COS81E、CLS82E)などの信頼性の高い
インラインおよびリアルタイム測定技術によって、世界トップクラ
スのバイオ医薬品メーカーから信頼されている理由を強調したグラ
フィック。Language:
Japanese
Version:
04/10/2024
File size:
2.7 MB
File name:
PU01585CJA_0124_Graphic_EH biopharma trust.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
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PU (Publication)
English version - 06/2024Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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-
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PU (Publication)
Biopharma 4.0 model graphic (full version)
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PU (Publication)
English version - 05/2025Expanded version of a graphic illustrating the core elements of
Biopharma 4.0 including product lifecycle stages, role of
PAT/QbD, and 12 key advanced technologies for scientists and
process engineers in the Life Sciences, applicable to Raman
spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10,
Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow
bench, Raman optic system for single use, and Raman calibration
& verification kits).Language:
English
Version:
22/05/2025
File size:
29.1 MB
File name:
PU01613CEN_0125.pdf
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PU (Publication)
効率的なバイオ医薬品の製品開発ライフサイクルのために拡張性を優先
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PU (Publication)
Japanese version - 10/2024この技術文書では、ライフサイエンス産業におけるバイオプロセス
の競争優位性としての拡張性の重要性と、Endress+Hauserの拡張性
のあるラマンシステム(Raman Rxn2、Raman Rxn4、Rxn-10、Rxn-45
、Rxn-46、バイオマルチオプティックおよびスリーブ、フローフィ
ル、フローベンチ、シングルユース用Ramanオプティックシステム)
、水質分析センサ技術、および水質分析製品ラインナップ
(LiquilineCM44P、CM442、OUSAF44、OUSBT66、Memosens CPS61E、
CLS82E、COS81E、CLS82E)について考察しています。Language:
Japanese
Version:
04/10/2024
File size:
1.3 MB
File name:
PU01584CJA_0124_Scalability in biopharma development.pdf
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